49 CFR § 391.41 — Physical qualifications for drivers. | Electronic Code of Federal Regulations (e-CFR) | US Law
§ 391.41 Physical qualifications for drivers.
(a)
(1)
(i) A person subject to this part must not operate a commercial motor vehicle unless he or she is medically certified as physically qualified to do so, and, except as provided in paragraph (a)(2) of this section, when on-duty has on his or her person the original, or a copy, of a current medical examiner’s certificate that he or she is physically qualified to drive a commercial motor vehicle. NOTE: Effective December 29, 1991, and as amended on January 19, 2017, the FMCSA Administrator determined that the Licencia Federal de Conductor issued by the United Mexican States is recognized as proof of medical fitness to drive a CMV. The United States and Canada entered into a Reciprocity Agreement, effective March 30, 1999, recognizing that a Canadian commercial driver’s license is proof of medical fitness to drive a CMV. Therefore, Canadian and Mexican CMV drivers are not required to have in their possession a medical examiner’s certificate if the driver has been issued, and possesses, a valid commercial driver license issued by the United Mexican States, or a Canadian Province or Territory, and whose license and medical status, including any waiver or exemption, can be electronically verified. Drivers from any of the countries who have received a medical authorization that deviates from the mutually accepted compatible medical standards of the resident country are not qualified to drive a CMV in the other countries. For example, Canadian drivers who do not meet the medical fitness provisions of the Canadian National Safety Code for Motor Carriers but are issued a waiver by one of the Canadian Provinces or Territories, are not qualified to drive a CMV in the United States. In addition, U.S. drivers who received a medical variance from FMCSA are not qualified to drive a CMV in Canada.
(ii) A person who qualifies for the medical examiner’s certificate by virtue of having obtained a medical variance from FMCSA, in the form of an exemption letter or a skill performance evaluation certificate, must have on his or her person a copy of the variance documentation when on-duty.
(2) CDL/CLP exception. (i)(A) Beginning on January 30, 2015 and through June 22, 2025, a driver required to have a commercial driver’s license under part 383 of this chapter, and who submitted a current medical examiner’s certificate to the State in accordance with 49 CFR 383.71(h) documenting that he or she meets the physical qualification requirements of this part, no longer needs to carry on his or her person the medical examiner’s certificate specified at § 391.43(h), or a copy, for more than 15 days after the date it was issued as valid proof of medical certification.
(B) On or after June 23, 2025, a driver required to have a commercial driver’s license or a commercial learner’s permit under 49 CFR part 383, and who has a current medical examiner’s certificate documenting that he or she meets the physical qualification requirements of this part, no longer needs to carry on his or her person the medical examiner’s certificate specified at § 391.43(h).
(ii) Beginning on July 8, 2015, and through June 22, 2025, a driver required to have a commercial learner’s permit under part 383 of this chapter, and who submitted a current medical examiner’s certificate to the State in accordance with § 383.
71(h) of this chapter documenting that he or she meets the physical qualification requirements of this part, no longer needs to carry on his or her person the medical examiner’s certificate specified at § 391.43(h), or a copy for more than 15 days after the date it was issued as valid proof of medical certification.
(iii) A CDL or CLP holder required by § 383.71(h) of this chapter to obtain a medical examiner’s certificate, who obtained such by virtue of having obtained a medical variance from FMCSA, must continue to have in his or her possession the original or copy of that medical variance documentation at all times when on-duty.
(iv) In the event of a conflict between the medical certification information provided electronically by FMCSA and a paper copy of the medical examiner’s certificate, the medical certification information provided electronically by FMCSA shall control.
(3) A person is physically qualified to drive a commercial motor vehicle if:
(i) That person meets the physical qualification standards in paragraph (b) of this section and has complied with the medical examination requirements in § 391.
43; or
(ii) That person obtained from FMCSA a medical variance from the physical qualification standards in paragraph (b) of this section and has complied with the medical examination requirement in § 391.43.
(b) A person is physically qualified to drive a commercial motor vehicle if that person —
(1) Has no loss of a foot, a leg, a hand, or an arm, or has been granted a skill performance evaluation certificate pursuant to § 391.49;
(2) Has no impairment of:
(i) A hand or finger which interferes with prehension or power grasping; or
(ii) An arm, foot, or leg which interferes with the ability to perform normal tasks associated with operating a commercial motor vehicle; or any other significant limb defect or limitation which interferes with the ability to perform normal tasks associated with operating a commercial motor vehicle; or has been granted a skill performance evaluation certificate pursuant to § 391.49;
(3) Has no established medical history or clinical diagnosis of diabetes mellitus currently treated with insulin for control, unless the person meets the requirements in § 391.
46;
(4) Has no current clinical diagnosis of myocardial infarction, angina pectoris, coronary insufficiency, thrombosis, or any other cardiovascular disease of a variety known to be accompanied by syncope, dyspnea, collapse, or congestive cardiac failure;
(5) Has no established medical history or clinical diagnosis of a respiratory dysfunction likely to interfere with his/her ability to control and drive a commercial motor vehicle safely;
(6) Has no current clinical diagnosis of high blood pressure likely to interfere with his/her ability to operate a commercial motor vehicle safely;
(7) Has no established medical history or clinical diagnosis of rheumatic, arthritic, orthopedic, muscular, neuromuscular, or vascular disease which interferes with his/her ability to control and operate a commercial motor vehicle safely;
(8) Has no established medical history or clinical diagnosis of epilepsy or any other condition which is likely to cause loss of consciousness or any loss of ability to control a commercial motor vehicle;
(9) Has no mental, nervous, organic, or functional disease or psychiatric disorder likely to interfere with his/her ability to drive a commercial motor vehicle safely;
(10)
(i) Has distant visual acuity of at least 20/40 (Snellen) in each eye without corrective lenses or visual acuity separately corrected to 20/40 (Snellen) or better with corrective lenses, distant binocular acuity of at least 20/40 (Snellen) in both eyes with or without corrective lenses, field of vision of at least 70° in the horizontal meridian in each eye, and the ability to recognize the colors of traffic signals and devices showing standard red, green, and amber; or
(ii) Meets the requirements in § 391.
44, if the person does not satisfy, with the worse eye, either the distant visual acuity standard with corrective lenses or the field of vision standard, or both, in paragraph (b)(10)(i) of this section;
(11) First perceives a forced whispered voice in the better ear at not less than 5 feet with or without the use of a hearing aid or, if tested by use of an audiometric device, does not have an average hearing loss in the better ear greater than 40 decibels at 500 Hz, 1,000 Hz, and 2,000 Hz with or without a hearing aid when the audiometric device is calibrated to American National Standard (formerly ASA Standard) Z24.5 — 1951;
(12)
(i) Does not use any drug or substance identified in 21 CFR 1308.11 Schedule I, an amphetamine, a narcotic, or other habit-forming drug; or
(ii) Does not use any non-Schedule I drug or substance that is identified in the other Schedules in 21 CFR part 1308 except when the use is prescribed by a licensed medical practitioner, as defined in § 382.
107 of this chapter, who is familiar with the driver’s medical history and has advised the driver that the substance will not adversely affect the driver’s ability to safely operate a commercial motor vehicle; and
(13) Has no current clinical diagnosis of alcoholism.
[35 FR 6460, Apr. 22, 1970]
Editorial Note:
For Federal Register citations affecting § 391.41, see the List of CFR Sections Affected, which appears in the Finding Aids section of the printed volume and at www.govinfo.gov.
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
. 1998 Feb 19;391(6669):806-11.
doi: 10.1038/35888.
A Fire
1
, S Xu, M K Montgomery, S A Kostas, S E Driver, C C Mello
Affiliations
Affiliation
- 1 Carnegie Institution of Washington, Department of Embryology, Baltimore, Maryland 21210, USA.
[email protected]
-
PMID:
9486653
-
DOI:
10.1038/35888
A Fire et al.
Nature.
.
. 1998 Feb 19;391(6669):806-11.
doi: 10.1038/35888.
Authors
A Fire
1
, S Xu, M K Montgomery, S A Kostas, S E Driver, C C Mello
Affiliation
- 1 Carnegie Institution of Washington, Department of Embryology, Baltimore, Maryland 21210, USA. fire@mail1.
ciwemb.edu
-
PMID:
9486653
-
DOI:
10.1038/35888
Abstract
Experimental introduction of RNA into cells can be used in certain biological systems to interfere with the function of an endogenous gene. Such effects have been proposed to result from a simple antisense mechanism that depends on hybridization between the injected RNA and endogenous messenger RNA transcripts. RNA interference has been used in the nematode Caenorhabditis elegans to manipulate gene expression. Here we investigate the requirements for structure and delivery of the interfering RNA. To our surprise, we found that double-stranded RNA was substantially more effective at producing interference than was either strand individually.
After injection into adult animals, purified single strands had at most a modest effect, whereas double-stranded mixtures caused potent and specific interference. The effects of this interference were evident in both the injected animals and their progeny. Only a few molecules of injected double-stranded RNA were required per affected cell, arguing against stochiometric interference with endogenous mRNA and suggesting that there could be a catalytic or amplification component in the interference process.
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Team | «Yenisey Kino» — film chronicle, film distribution, film production in the Krasnoyarsk Territory
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The results of the annual regional competition «Best in Profession»
Yesterday, on August 26, 2021, the final of the annual regional competition of professional skills «Best in Profession» took place in eleven nominations, and the results were also summed up voting for the title of the best worker in four nominations. nine0621 — Head of the Service Administration «Kanskmezhraigaz»
Professional professional
Pinigin Nikolay Viktorovich — Deputy Chief Engineer — Head of the emergency operation of the emergency operation and emergency service
9000
9000 Best Capital of MCD (Electrigate.
and mechanic for the operation and repair of gas equipment)
Romanovich Vyacheslav Mikhailovich — a locksmith for the operation and repair of gas equipment 3 categories 3 of the overhaul of MKD
Sergeev Ivan Sergeevich Electric Gas welder 3 categories MCD Capital Repair
Emergency and Emergency work (brigade)
9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 9000 — the driver of the vehicle (ADS)0011
Grack Aleksey Alekseevich — driver of the car (1 gr. Gruz. From 5 to 7 TN) Settling networks of the Kansky gas station «Kanskemezhraigaz»
Locabulary for the operation and repair of underground gas pipelines (brigade)
Kozlov Roman Olegovich — mechanic for the operation and repair of gas equipment of the 5th category0011
Ribrik Nikita Aleksandrovich -locksmith for the operation and repair of gas equipment 5 category Settings of the installation, repair and operation of gas equipment of the emergency and operational service
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9000 Yevgeny Gennadievich — drivers — drivers ( 3 gr.